COMBINATIONAL APPROACH USING SOLID DISPERSION AND SEMI-SOLID MATRIX TECHNOLOGY TO ENHANCE IN VITRO DISSOLUTION OF TELMISARTAN

Combinational approach using solid dispersion and semi-solid matrix technology to enhance in vitro dissolution of telmisartan

The present investigation was focused to formulate semi-solid capsules (SSCs) of hydrophobic drug telmisartan (TLMS) by encapsulating semi-solid matrix of its solid dispersion (SD) in HPMC capsules.The combinational approach was used to reduce the lag time in drug release and improvise its dissolution.SDs of TLMS was prepared using hot fusion metho

read more

Philanthro-metrics: Mining multi-million-dollar gifts.

The Million Dollar List (MDL, online at http://www.milliondollarlist.org) is a compilation of publicly announced charitable donations of $1 million or more from across the United States since 2000; as of December 2016, the database contains close to 80,000 gifts made by U.S.individuals, corporations, foundations, and other grant-making nonprofit or

read more

Optimization of hoisting parameters in a multi-rope friction mine hoist based on the multi-source coupled vibration characteristics of hoisting catenaries

To avoid catenary collision in a multi-rope friction mine hoist, in this study, the relevant hoisting parameters based on the multi-source coupled vibration characteristics of hoisting Keto Supplements catenaries are optimized.First, the multi-source coupled vibration characteristics of hoisting catenaries were investigated based on an established

read more


Recent progress on anti-cancer activity of thiadiazoles: A review

Cancer, a life-threatening condition which has become one of the deadliest disease impacting human health.Conventional drugs have significant side effects and are prone to drug resistance, whereas innovative therapies are costly and place a large load on patients.Despite the fact that several decades of medication research and discovery have produc

read more